Extraction and structured synthesis
Group and summarize eligible evidence
This flow is structured synthesis of quantitative evidence. A qualitative evidence synthesis needs different analytic methods; it is not automatically supplied by this starter. Preserve effect magnitude and uncertainty where available.
Flow diagram
Steps
Pilot extraction and charting
Define independent verification and linkage of reports to studies.
Define synthesis groups
Group designs, populations, interventions, outcomes and time points explicitly.
Prioritize outcomes and measures
Prespecify selection when a study reports several measures or time points.
Specify structured synthesis
Explain why pooling is unsuitable and choose transparent synthesis methods.
Handle conflicting findings
Examine direction, magnitude, precision, context and limitations rather than counting significant results.
Plan evidence presentation
Specify tables and displays with provenance and uncertainty.
Extraction and structured synthesis
End flow
Tables and supporting information
Extraction and grouping register
Retain study-level contributions.
Synthesis plan
Document presentation and interpretation rules.
Interpretation rules
Absence of statistical significance is not evidence of no effect. Avoid significance-based vote counting.