Platform cohort and arm eligibility

Match participants to eligible comparisons

Master eligibility does not guarantee eligibility for every arm. Preserve arm-specific eligibility and available options at each entry date before defining comparison populations.

Flow diagram

Steps

Define master and cohort eligibility

Specify shared criteria and distinct cohort definitions.

Assess intervention-specific eligibility

Record contraindications and eligibility for each active comparison.

Identify available arms by epoch

Use arm opening and closure dates at participant entry.

Define eligible comparison sets

Retain the interventions among which each person could have been randomized.

Track enrollment and exclusions

Preserve cohort, arm eligibility and calendar epoch without conflating overlapping groups.