Paired t-test

Hypothesis tests · Method and input reference

Two-sided; independent t uses Welch. Paired tests require matched observations. Permutation uses difference in means, 9,999 resamples and a fixed seed. Effect sizes use pooled sample SD. Synthetic example: 120 matched baseline and week-12 blood pressures (mmHg). Row positions identify the same person; responses vary and some worsen.

Open calculator · Compare methods in the decision matrix

When to consider it

  • Two dependent observations per unit, continuous outcome with approximately normal differences.

Assumptions and scope

  • Each observation must be matched to the same subject or unit in the other sample.
  • Pairs must be independent. Assess the distribution of within-pair differences, especially with small samples.

Required inputs

  • Observations — Numeric observations; preserve the row and column structure described above.
  • Second sample — Numeric observations; preserve the row and column structure described above.

Review missing values and data coding before running. Sample inputs are synthetic teaching examples.

Implementation

Lifescio validates inputs and formats results; listed functions are the principal calculation routines, not an exhaustive transitive dependency list.

  • scipy 1.15.3: scipy.stats.ttest_rel

These are pinned library versions; saved results record the versions actually used at runtime.

Library references