Independent t-test

Hypothesis tests · Method and input reference

Two-sided; independent t uses Welch. Paired tests require matched observations. Permutation uses difference in means, 9,999 resamples and a fixed seed. Effect sizes use pooled sample SD. Synthetic example: Two independent blood-pressure cohorts: 120 and 96 people, with unequal variability; values in mmHg.

Open calculator · Compare methods in the decision matrix

When to consider it

  • Compare means in two independent groups with Welch’s t-test.

Assumptions and scope

  • Observations must be independent between subjects; repeated rows from one subject are not independent samples.
  • Check outliers and whether mean-based inference is suitable for the sample sizes and distributions. Do not select a test solely from a normality-test p-value.

Uses Welch; no pooled-variance option.

Required inputs

  • Observations — Numeric observations; preserve the row and column structure described above.
  • Second sample — Numeric observations; preserve the row and column structure described above.

Review missing values and data coding before running. Sample inputs are synthetic teaching examples.

Implementation

Lifescio validates inputs and formats results; listed functions are the principal calculation routines, not an exhaustive transitive dependency list.

  • scipy 1.15.3: scipy.stats.ttest_ind

These are pinned library versions; saved results record the versions actually used at runtime.

Library references